Leveraging input and output structures for joint mapping of epistatic and marginal eQTLs
نویسندگان
چکیده
منابع مشابه
Leveraging input and output structures for joint mapping of epistatic and marginal eQTLs
MOTIVATION As many complex disease and expression phenotypes are the outcome of intricate perturbation of molecular networks underlying gene regulation resulted from interdependent genome variations, association mapping of causal QTLs or expression quantitative trait loci must consider both additive and epistatic effects of multiple candidate genotypes. This problem poses a significant challeng...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2012
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/bts227